The influence of calcium signaling on the regulation of alternative splicing.
نویسنده
چکیده
In this review the influence of calcium signaling on the regulation of alternative splicing is discussed with respect to its influence on cell- and developmental-specific expression of different isoforms of the plasma membrane calcium pump (PMCA). In a second part the possibility is discussed that due to the interaction of the calcium-binding protein ALG-2 with a spliceosomal regulator of alternative splicing, RBM22, Ca2+-signaling may thus influence its regulatory property.
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عنوان ژورنال:
- Biochimica et biophysica acta
دوره 1793 6 شماره
صفحات -
تاریخ انتشار 2009